|| Veena Group of Hospitals ||

Dr. Ashay H. Nandeshwar
M. D., (Ayu)(Mumbai)
(Podar Govt. Medical College)
P.G.D.M.L.T., L.Lb. (Sch)
Lecturer V.P.A.M.C.
Sangli

Sikle Cell Anaemia & Multiple Drug Resistance i.e. M.D.R.

M.D.R. is term with which every doctor is familiar and every doctor is encountering challenges against M.D.R.

What is M.D.R. ?
M.D.R. is a state were a patient does not respond to classical group of medicine or regularly used antibiotics or lower generation of Antibiotics.

What causes M.D.R. ?

1	All the Antibiotics should be prescribed by doctors.
2	Antibiotics should be in proper per kilogram body weight proportion and it should be in proper course of time period, but many times some doctors prescribe Antibiotics in lower doses or in improper dose.
3	Some of the people who consider themselves as doctors and directly bring medicines from the Pharmacists.
4	Some people directly purchase medicines from Pharmacists on pharmacist’s advice as counter sale.
5	People who don’t take the medicines as per doses or prescription are responsible to cause M.D.R.

Because of such reasons the pathogen or Bacteria becomes resistant to the Antibiotics and they are not completely eradicated i.e. it does not respond to the standard medication.

How M.D.R. is related with Sickle Cell Anaemia patient?
Sickle Cell Anaemia patients suffering increases in infection so if a patient is having M.D.R. then they will not respond to their regular Antibiotics and he will have to get hospitalized and will have to put on higher generation of Antibiotics.

So if Sickle Cell Anaemic patient wants to lead a healthy life then they will have to take proper medication as advised by the proper Registered Doctor and should follow the proper course of treatment.

They should not teke self medication because it can cost their life.

Case:
One of my patient name unexposed due to medical ethics, his father used to tamper with
the doses of Antibiotics, few months back he started getting frequent attack of fever, his father used to rush at me and used to shout at me. Then one day I scold him and convince him that his son in having M.D.R. and he is not responding to cefexime he will have to start higher generation of Antibiotics. Then I took appointment of Dr. Sakhare from Wockhardt Hospital and started higher generation of the medicine and today the patient is completely well.

How to prevent M.D.R.?

1	Follow the instruction of your doctor.
2	Don’t take Antibiotics on your own.
3	Don’t stop Antibiotics yourself.
4	Don’t purchase Antibiotics directly from pharmacists.
5	Though after getting relief from the symptoms of the illness don’t suddenly stop the medicines finish the complete course.

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